Found 15 matching trials
Pilot Study of Autologous Anti-EGFRvIII CAR T Cells in Recurrent Glioblastoma Multiforme PHASE1 Chimeric antigen receptor (CAR)-modified T cells can mediate long-term dura...
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Sanbo Brain Hospital Capital Medical University
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Biomarker-Guided Dual-Target CAR-T Cells for Advanced Solid Tumors PHASE1 This is a multicenter, open-label, Phase 1/2 master protocol evaluating aut...
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Peking University Shenzhen Hospital
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Evaluate the Safety and Efficacy of CAR-T in the Treatment of Pancreatic Cancer. EARLY_PHASE1 Immunotherapy has become the major breakthrough and the most promising trea...
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Harbin Medical University
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A Study to Evaluate the Safety, Tolerance and Initial Efficacy of EGFRvIII CAR-T on Glioblastoma EARLY_PHASE1 This is a single-center, open, dose-increasing study. For subjects with rec...
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Multiple Locations
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The Efficacy and Safety of Brain-targeting Immune Cells (EGFRvIII-CAR T Cells) in Treating Patients With Leptomeningeal Disease From Glioblastoma. Administering Patients EGFRvIII -CAR T Cells May Help to Recognize and Destroy Brain Tumor Cells in Patients PHASE1 This phase I trial investigates the efficacy and safety of brain-targeting ...
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Jyväskylä Central Hospital
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Autologous T Cells Redirected to EGFRVIII-With a Chimeric Antigen Receptor in Patients With EGFRVIII+ Glioblastoma PHASE1 An Open-Label Phase 1 Pilot Study to determine the safety and feasibility o...
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Anti-EGFRvIII synNotch Receptor Induced Anti-EphA2/IL-13Ralpha2 CAR (E-SYNC) T Cells PHASE1 This phase I trial tests the safety, side effects, and best dose of E-SYNC ...
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University of California, San Francisco
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Autologous CAR-T/TCR-T Cell Immunotherapy for Solid Malignancies PHASE1 This is a single arm, open-label, uni-center, phase I-II study to evaluate ...
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Henan Provincial People's Hospital
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Intracerebral EGFR-vIII CAR-T Cells for Recurrent GBM PHASE1 The goal of this protocol is to transfer autologous peripheral blood mononu...
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Duke University Medical Center
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CARv3-TEAM-E T Cells in Glioblastoma PHASE1 The goal of this research study is to determine the best dose of CARv3-TEAM...
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Massachusetts General Hospital Cancer Center
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